Clinical Trials for Carotid Artery Disease

Carotid Revascularization Endarterectomy vs. Stent Trial (CREST)
Contrasts the relative efficacy of Carotid Artery Stenting (CAS) versus Carotid Endarterectomy (CEA) in preventing stroke, myocardial infarction, and death in patients with symptomatic and asymptomatic extracranial carotid stenosis.

Asymptomatic Carotid Stenosis, Stenting vs. Endarterectomy Trial (ACT 1)
Seeks to demonstrate that carotid artery stenting using the Emboshield Cerebral Protection System with the Xact RX Carotid Stent System is equally effective to carotid endarterectomy in treating asymptomatic extracranial carotid stenotic disease.

The Embolic Protection with Reverse Flow (EMPiRE) Study of the GORE Neuro Protection System in Carotid Stenting of Subjects at High Risk for Carotid Endarterectomy
Assesses the safety and effectiveness of the GORE Neuro Protection System in providing embolic protection during carotid artery angioplasty and stenting procedures in high-risk surgical subjects.

Clinical Trials for Arterial Aneurysms

Open to Enrollment:

Study of Thoracic Aortic Aneurysm Repair with the Zenith® TX2™ TAA [Thoracic Aortic Aneurysm] Endovascular Graft
An extended investigation to continue to collect data regarding the safety and effectiveness of the Zenith TX2 TAA Endovascular Graft in the treatment of descending thoracic aortic aneurysms.

Valor II: The Valiant Thoracic Stent Graft System Clinical Study
Evaluation of a device used to treat patients with descending thoracic aneurysms of degenerative etiology who are candidates for endovascular repair. Information will be collected on the performance of the device for 5 years.

Closed to enrollment, follow-up only:

Evaluation of the Medtronic Vascular Talent Thoracic Stent Graft System for Treatment of Thoracic Aortic Aneurysms
5-year follow-up for patients who have had an endovascular repair of a descending thoracic aneurysm with the Talent Thoracic Stent Graft System.